Photo: Bjørn-Kåre Iversen
Ole Morten Seternes
Job description
Professor i Farmakologi og gruppeleder for forskningsgruppen i Celle signallering og målrettet terapi. Emneleder for Farmakologi
Maria,
Ingvild,
Terje,
Ole Morten,
Jakob
:
Low extracellular pH protects cancer cells from ammonia toxicity
Cell death discovery 2025 DOI
Fadia,
Mathilde,
Natalia,
Anneke,
Alexey,
Ole Morten
et al.:
On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer
Erik,
Saikat Das,
Tonje,
James Bradley,
Thorarinn,
Gunhild Mari
et al.:
Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
Benedicte Sjo,
Monica,
Oda Helen Eck,
Stein-Erik,
Aashish,
Even
et al.:
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Lisa Zeyen,
Ole Morten,
Ingvild
:
Crosstalk between p38 MAPK and GR Signaling
Joaquim,
Eugénie,
Mathilde,
Evgeny,
Antoine,
Ole Morten
et al.:
Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy
Dennis,
Linn,
Yorick Andreas van der,
Ingvill,
Ole Morten,
Jorunn
:
Infection and microbial molecular motifs modulate transcription of the interferon-inducible gene ifit5 in a teleost fish
Anup,
Henrike,
Hanne,
Gurjit,
Matthias,
Hilde Ljones
et al.:
Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38 MAPK-MK2 axis and affects NF-κB-mediated transcription
Ole Morten,
Andrew M,
Stephen M
:
Dual-specificity MAP kinase phosphatases in health and disease
Anna Lucja,
Wang,
Diana,
Yao,
Xianming,
Hwan Geun
et al.:
Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors
Maria,
Rania,
Thomas Clemens,
Jennifer Ann Lillebo,
Hanne,
Bjarne Herold
et al.:
Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2
Sampada Satchidanand,
Anett Kristin,
Ole Morten,
Berit
:
Mixed exposure to bacterial lipopolysaccharide and seafood proteases augments inflammatory signalling in an airway epithelial cell model (A549)
Jennifer L.,
Leah,
Katherine A,
Paula,
Janani,
Ole Morten
et al.:
AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2016 DOI
Tonje,
Erik,
Malene,
Tor Erik,
Steinar Daae,
maria
et al.:
Distinct small RNA signatures in extracellular vesicles derived from breast cancer cell lines
Maria,
Stephen M,
Ole Morten
:
New insights into the activation, interaction partners and possible functions of MK5/PRAK
Frontiers in Bioscience 2016
Ka,
Naveen Reddy,
Lobna,
Wei,
Cheng,
Tenghui
et al.:
ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells
Rania,
Nouf,
Kiruthikah,
Mark,
Bjarne Herold,
Hilde Ljones
et al.:
A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration
Cell Adhesion & Migration 2015 DOI
Jennifer L.,
Patrick J.,
Brian J.,
Lorene K.,
Ole Morten,
John D.
:
Protein kinase A opposes the phosphorylation-dependent recruitment of glycogen synthase kinase 3β to A-kinase Anchoring Protein 220
Sampada Satchidanand,
Anett Kristin,
Jan-Olof,
Ole Morten,
Berit
:
Salmon and king crab trypsin stimulate interleukin-8 and matrix metalloproteinases via protease-activated receptor-2 in the skin keratinocytic HaCaT cell line
Food and Chemical Toxicology (FCT) 2014 DOI
Erik,
Tonje,
anita,
Tor Erik,
maria,
Eiliv
et al.:
Performance Comparison of Digital microRNA Profiling Technologies Applied on Human Breast Cancer Cell Lines
Anett Kristin,
kurt,
Ingebrigt,
Ole Morten,
Berit
:
Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin
Ilona,
Bård Ove,
Siri,
Ole Morten,
Steinar,
Åse
:
Digital Marine Bioprospecting: Mining New Neurotoxin Drug Candidates from the Transcriptomes of Cold-Water Sea Anemones
Anett Kristin,
ole morten,
Merethe,
Hideki,
Galina N,
Berit
:
Purified sardine and king crab trypsin display individual differences in PAR-2-, NF-kappa B-, and IL-8 signaling
ole morten,
Bjarne Herold,
Beate,
Mona,
Stephen M,
Ugo
:
Both Binding and Activation of p38 Mitogen-Activated Protein Kinase (MAPK) Play Essential Roles in Regulation of the Nucleocytoplasmic Distribution of MAPK-Activated Protein Kinase 5 by Cellular Stress
Molecular and Cellular Biology 2010 DOI
Steinar D.,
Åse,
Bård Ove,
Siri,
Hilde,
Truls
et al.:
Approaching marine bioprospecting in hexacorals by RNA deep sequencing
New Biotechnology 2010 DOI
espen,
Knut Martin,
Bjarne Herold,
Stephen M,
maria,
ole morten
:
Docking of PRAK/MK5 to the Atypical MAPKs ERK3 and ERK4 Defines a Novel MAPK Interaction Motif
Journal of Biological Chemistry 2009 DOI
Anett Kristin,
ole morten,
Merethe,
lisbeth,
Berit
:
Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2
Toxicology and Applied Pharmacology 2008 DOI
Tom Egil,
Pål,
A.W.,
ole morten,
Gerald,
Jorunn B
et al.:
Atlantic salmon possess three mitogen activated protein kinase kinase 6 paralogs responding differently to stress
The FEBS Journal 2008 DOI
maria,
espen,
Bjarne Herold,
Bo,
Ingrid Jenny,
heidi
et al.:
The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5
Biochemical Journal 2008 DOI
maria,
Stephen M,
ole morten
:
Does MK5 reconcile classical and atypical MAP kinases?
Frontiers in Bioscience 2008
espen,
maria,
Bjarne Herold,
Catherine,
Sylvain,
Stephen M
et al.:
Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4
Journal of Biological Chemistry 2006
Ole Morten,
Theresa,
Bjarne,
Espen,
CG,
NA
et al.:
Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway
EMBO Journal 2004 DOI
Mona,
Marit Pedersen,
Ole Morten,
Bjarne,
Ugo Lionel
:
Synergistic activation of CREB-mediated transcription by forskolin and phorbol ester requires PKC and depends on the glutamine-rich Q2 transactivation domain
Cellular Signalling 2004
Nico,
Cédric,
Ugo,
ole morten,
Peter De,
Jackie R
:
Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells
Journal of Biological Chemistry 2004
Mona,
Petter Angell,
Bjarne,
Ole Morten,
Ugo Lionel
:
Activation of the coactivator foru-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A
Biochemical Pharmacology 2003
Nico,
Cédric,
Ugo Lionel,
Ole Morten,
Peter De,
Jackie R
et al.:
Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells
Journal of Biological Chemistry 2003 DOI
Benedicte Sjo,
Monica,
Oda Helen Eck,
Stein-Erik,
Aashish,
Even
et al.:
Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia (Nature Communications, (2023), 14, 1, (115), 10.1038/s41467-022-35624-4)
Nature Communications 2023 DOI
Berit,
Anett Kristin,
Sampada Satchidanand,
Nabin,
Ole Morten,
Jan-Olof
:
Seafood proteases present in workplace bioaerosols – effects on inflammatory pathways in skin and airway cell models.
2016
Berit,
Anett Kristin,
Sampada Satchidanand,
Nabin,
Ole Morten,
Jan-Olof
:
Seafood proteases present in workplace bioaerosols – effects on inflammatory pathways in skin and airway cell models.
2016
espen,
Ole Morten,
Richard Alan,
Franz
:
Fra Mutasjon til Medisin
2013
Anett Kristin,
Merethe,
Ole Morten,
Berit
:
Proteases in Seafood as activators of inflammatory reactions in airway epithelial cells
2011
maria,
Trine,
Lene Elisabeth,
Espen,
ole morten,
Lars
et al.:
Characterization of cytotoxic activities in extracts from two marine invertebrates
2011
Erik,
morten,
Tonje,
anita,
Eiliv,
Ole Morten
et al.:
MiRNA expression profiling based on different high-throughput
platforms reveals surprising variations
2011
Steinar Daae,
morten,
Igor,
Teshome,
Dag-Hugo,
M. Raafat
et al.:
Investigating miRNAs and transcriptomes at our local SOLiD sequencing facility
2011
Anett Kristin,
Berit,
Ole Morten
:
Proteases from seafood as activators of protease-activated receptor-2 in airway epithelial cells
UiT Norges arktiske universitet 03. décembre 2010
Anett Kristin,
Merethe,
Ole Morten,
Berit
:
Protease-activated signal pathways in airway cells. Purified salmon trypsin activates Nuclear factor kappa-B and induces interleukin-8 secretion in human airway epithelial cells (A549)
2007
Merethe,
Berit,
ole morten,
Anett K.
:
Protease-activated signal pathways in airway cells. Purified salmon trypsin activates nuclear factor kappa-B and induces interleukin-8 secretion in human airway epithelial cells (A549)
Allergy. European Journal of Allergy and Clinical Immunology 2007
Espen,
maria,
Bjarne Herold,
Catherine,
Sylvain,
Stephen M
et al.:
Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAP kinase ERK4/MAPK4
2006
ole morten
:
The atypical MAP kinases ERK3 and 4 defines novel signaling pathways
2006
ole morten
:
The atypical MAP kinases ERK3 and 4 defines novel signaling pathways
2006
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Teaching
Underviser i emnene FAR2206 og FAR2207.