Sigrid Kufaas Brækkan
Job description
Professor, Tromboseforskning (TREC)
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
Ellisiv B. Mathiesen,
Maja-Lisa Løchen,
Tom Wilsgaard,
Kristian Hveem
et al.:
Impact of ischemic stroke on the risk of venous thromboembolism in the general population: the Tromsø Study and the Trøndelag Health Study
Vårin Eiriksdatter Wikan,
Øyvind Øverli,
Thor Ueland,
Tom Eirik Mollnes,
Sigrid Kufaas Brækkan,
Annika Elisabet Michelsen
et al.:
Complement activation assessed by C3bc and C5b-9 terminal complex as diagnostic biomarkers for deep vein thrombosis
Samantha Xavier,
Vårin Eiriksdatter Wikan,
Casper J.E. Wahlund,
Nadezhda Latysheva,
Øyvind Øverli,
Christopher Antoun
et al.:
Total and extracellular vesicle–bound plasma P-selectin as diagnostic biomarkers for acute deep vein thrombosis
Erin Mathiesen Hald,
Maja-Lisa Løchen,
Kristian Hveem,
Mary Cushman,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
Joint effects of atrial fibrillation and prothrombotic genotypes on the risk of venous thromboembolism
Christopher Antoun,
Julia Oto,
Vania Maris Morelli,
Kristian Hveem,
Sigrid Kufaas Brækkan,
Pilar Medina
et al.:
Plasma miR-145-5p Levels and Risk of Future Cancer—Results from the HUNT Study
Carl-Arne Arnesen,
Kristian Hveem,
Maiken Elvestad Gabrielsen,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Body height and risk of venous thromboembolism in men vs women
Christabel Esi Damoah,
Solveig Marie Valderhaug,
Omri Snir,
Kristian Dalsbø Hindberg,
Sigrid Kufaas Brækkan,
Steven P. Grover
et al.:
Elevated Plasma MBL Levels Are Associated With Risk of Future Venous Thromboembolism: The HUNT Study
Nikolai Hagensen Eide,
Camilla Langholm,
Fridtjof Balteskard Rinde,
Nick van Es,
Kristian Hveem,
Sigrid Kufaas Brækkan
et al.:
Mortality risk after cancer-related venous thromboembolism has decreased over the last three decades: the HUNT and Tromsø studies
Oda Leknessund,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Resting Heart Rate and Risk of Incident Venous Thromboembolism: The Tromso Study
Erin Mathiesen Hald,
Maja-Lisa Løchen,
Ellisiv B. Mathiesen,
Kristian Hveem,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
Joint effects of atrial fibrillation and prothrombotic genotypes on the risk of ischemic stroke
Vania Maris Morelli,
Omri Snir,
Kristian Dalsbø Hindberg,
Kristian Hveem,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
High microRNA-145 plasma levels are associated with decreased risk of future incident venous thromboembolism: the HUNT study
Carl-Arne Arnesen,
Line Holtet Evensen,
Kristian Hveem,
Maiken Elvestad Gabrielsen,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women
Zygimantas Zaboras,
Camilla Tøvik Jørgensen,
Andreas Stensvold,
Heidi Hassel Pettersen,
Aleksandra Grdinic Galovic,
Sigrid Kufaas Brækkan
et al.:
Real-world Data on Treatment Patterns and Bleeding in Cancer-associated Thrombosis: Data from the TROLL Registry
Luuk J.J. Scheres,
Sigrid Kufaas Brækkan,
Judith P.L. Verlaan,
Suzanne C. Cannegieter,
John Bjarne Hansen,
Vania Maris Morelli
:
The fatty liver index and risk of incident venous thromboembolism: the Tromsø Study
Christopher Antoun,
Vårin Eiriksdatter Wikan,
Øyvind Øverli,
Thor Ueland,
Gholamreza Jafari Yeganeh,
Sigrid Kufaas Brækkan
et al.:
Plasma microRNA-145-5p as a diagnostic biomarker for acute deep vein thrombosis
Birgitte Gladsø Tøndel,
Joakim Knutsen Sejrup,
Vania Maris Morelli,
Maja-Lisa Løchen,
Inger Njølstad,
Ellisiv B. Mathiesen
et al.:
Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
Sigrid Kufaas Brækkan,
Asbjørn Lund Onsaker,
Therese Haugdahl Nøst,
Weihong Tang,
Kristian Dalsbø Hindberg,
Vania Maris Morelli
et al.:
The Plasma Proteome and Risk of Future Venous Thromboembolism—Results from the HUNT Study
Oda Leknessund,
Vania Maris Morelli,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Hand grip strength in venous thromboembolism: risk of recurrence and mortality
Monique J.T. Crobach,
Rayna J.S. Anijs,
Sigrid Kufaas Brækkan,
Marianne T. Severinsen,
Jens Hammerstrøm,
Hanne Skille
et al.:
Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
Maria A. De Winter,
Harry R. Büller,
Marc Carrier,
Alexander T. Cohen,
John Bjarne Hansen,
Karin A. H. Kaasjager
et al.:
Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
Ellen-Sofie Hansen,
Magnus Edvardsen,
Pål Aukrust,
Thor Ueland,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
et al.:
Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism
Dana Meknas,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Vania Maris Morelli
:
Surgery As a Trigger for Incident Venous Thromboembolism: Results from a Population-Based Case-Crossover Study
Samantha Swamy,
Thor Ueland,
John Bjarne Hansen,
Omri Snir,
Sigrid Kufaas Brækkan
:
Plasma levels of P-selectin and future risk of incident venous thromboembolism
Fridtjof Balteskard Rinde,
Camilla Tøvik Jørgensen,
Heidi Hassel Pettersen,
John Bjarne Hansen,
Waleed Ghanima,
Sigrid Kufaas Brækkan
:
Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
Tobias Frischmuth,
Birgitte Gladsø Tøndel,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Vania Maris Morelli
:
The Risk of Incident Venous Thromboembolism Attributed to Overweight and Obesity: The Tromso Study
Steven P. Grover,
Omri Snir,
Kristian Dalsbø Hindberg,
Tatianna M. Englebert,
Sigrid Kufaas Brækkan,
Vania Maris Morelli
et al.:
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
Steven P. Grover,
Tomohiro Kawano,
Jun Wan,
Pansakorn Tanratana,
Zsofia Polai,
Young J. Shim
et al.:
C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
Camilla Tøvik Jørgensen,
Sigrid Kufaas Brækkan,
Eli Førsund,
Heidi Hassel Pettersen,
Eirik Tjønnfjord,
Waleed Ghanima
et al.:
Incidence of venous thromboembolism, recurrence, and bleeding after isolated superficial vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
Camilla Tøvik Jørgensen,
Mazdak Tavoly,
Elise Førsund,
Heidi Hassel Pettersen,
Eirik Tjønnfjord,
Waleed Ghanima
et al.:
Incidence of bleeding and recurrence in isolated distal deep vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
Espen Waage Skjeflo,
Line Holtet Evensen,
Søren Beck Jensen,
Nadezhda Latysheva,
Annika Elisabet Michelsen,
Thor Ueland
et al.:
Complement factors B, D, C3bBbP and risk of future venous thromboembolism
loannis T. Farmakis,
Stefano Barco,
Lukas Hobohm,
Sigrid Kufaas Brækkan,
Jean M. Connors,
George Giannakoulas
et al.:
Maternal mortality related to pulmonary embolism in the United States, 2003–2020
Magnus Edvardsen,
Ellen-Sofie Hansen,
Thor Ueland,
Pål Aukrust,
Sigrid Kufaas Brækkan,
Vania Maris Morelli
et al.:
Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
Vårin Eiriksdatter Wikan,
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
Ellen Elisabeth Brodin,
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review
Sigrid Kufaas Brækkan,
John Bjarne Hansen
:
VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology
Joakim Knutsen Sejrup,
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
Maja-Lisa Løchen,
Inger Njølstad,
Ellisiv B. Mathiesen
et al.:
Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
Omri Snir,
line Wilsgård,
Nadezhda Latysheva,
Casper Ullsten-Wahlund,
Sigrid Kufaas Brækkan,
Kristian Dalsbø Hindberg
et al.:
Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
Oda Leknessund,
Vania Maris Morelli,
Bjørn Heine Strand,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
Christabel Esi Damoah,
Omri Snir,
Kristian Dalsbø Hindberg,
Peter Garred,
Judith K Ludviksen,
Sigrid Kufaas Brækkan
et al.:
High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
Elias Allarai,
Wei-Hsuan Lee,
Stephen Burgess,
Susanna C. Larsson,
Sara Lindstrom,
Lu Wang
et al.:
Genetically predicted cortisol levels and risk of venous thromboembolism
Birgitte Gladsø Tøndel,
Vania Maris Morelli,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
Line Holtet Evensen,
Carl-Arne Arnesen,
Frits Richard Rosendaal,
Maiken Elvestad Gabrielsen,
Ben Michael Brumpton,
Kristian Hveem
et al.:
The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
Camilla Tøvik Jørgensen,
Mazdak Tavoly,
Heidi Hassel Pettersen,
Eli Førsund,
Christina Roaldsnes,
Magnus Kringstad Olsen
et al.:
The venous thrombosis registry in Østfold Hospital (TROLL registry) - design and cohort description
Lisa Jakobsen,
Tobias Frischmuth,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Vania Maris Morelli
:
Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
Aniket Mishra,
Rainer Malik,
Tsuyoshi Hachiya,
Tuuli Jürgenson,
Shinichi Namba,
Daniel C. Posner
et al.:
Stroke genetics informs drug discovery and risk prediction across ancestries
Helle Jørgensen,
Erzsébet Horváth-Puhó,
Kristina Laugesen,
Sigrid Kufaas Brækkan,
John Bjarne Hansen,
Henrik Toft Sørensen
:
The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
Birgitte Gladsø Tøndel,
Sigrid Kufaas Brækkan
:
The risk of venous thromboembolism after ischemic stroke
UiT Norges arktiske universitet 22. janvier 2026 ARKIV
Oda Leknessund,
Vania Maris Morelli,
Bjørn Heine Strand,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
:
Corrigendum to ‘Hand grip strength and risk of incident venous thromboembolism: The Tromsø study’: [Res Pract Thromb Haemost. 2022 Nov 4;6/7 e12833] (Research and Practice in Thrombosis and Haemostasis (2022) 6(7), (S2475037922024669), (10.1002/rth2.12833))
Ellen-Sofie Hansen,
Magnus Edvardsen,
Pål Aukrust,
Thor Ueland,
John Bjarne Hansen,
Sigrid Kufaas Brækkan
et al.:
Galectin-3-binding protein and future venous thromboembolism
Steven P. Grover,
Linda Sundler Björkman,
Sigrid Kufaas Brækkan,
Bengt Zöller,
John Bjarne Hansen,
Nigel Mackman
:
“C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study”: comment from Grover et al
Steven P. Grover,
Sigrid Kufaas Brækkan,
Nigel Mackman,
John Bjarne Hansen
:
“High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: reply
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Research interests
Klinisk epidemiologi og risikofaktorer for venøs tromboembolisme
Patofysiologi ved venøs tromboembolisme
Member of research group
Member of project
PREVENT
Mission-VTE
Milestone VTE
Genetics and VTE
PEPSI-VTE
Obesity-related VTE
Biomarkers of VTE risk
Diagnostic biomarkers of VTE
Cancer-associated VTE (CAT)
Sex-differences in VTE
Arterial and venous thrombosis
Life-style factors and VTE
VTE recurrence
Hypoxia-dependent proteins and VTE
Epidemiology of VTE
Risk of bleeding after VTE
CV
Utdanning/Grad
2010 PhD i Helsefag, Universitetet i Tromsø
2005 Master i Farmasi, Universitetet i Tromsø
Tidligere akademiske stillinger
2012-13 Postdoktor, Dep. of Clinical Epidemiology, Leiden University Medical Center, Nederland
2010-12 Postdoktor, Hematologisk forskningsgruppe, Universitetet i Tromsø (Helse-Nord midler)
2008-09 Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT
2006-08 PhD-student, Center for Atherothrombotic Research in Tromsø, UiT
2005-06 Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT
Publikasjoner
>185 fagfellevurderte originalartikler indeksert i PubMed. Har bidratt til mer enn 200 abstracts presentert og publisert i forbindelse med internasjonale vitenskapelige kongresser.
Andre relevante vitenskapelige verv
2021-2024: Associate Editor i Journal of Thrombosis and Haemostasis (JTH)
2016-dd: Metodologisk reviewer for Journal of Thrombosis and Haemostasis (JTH)
2016-2018: Medlem av junior advisory board for European Congress on Thrombosis and Haemostasis (ECTH)
Priser og utmerkelser
Young Investigator Award ISTH2016 (International Society of Thrombosis and Haemostasis)
Det Helsevitenskapelige Fakultets pris til yngre forsker 2017
Veiledning av PhD-studenter
Fullførte doktorgrader: Hovedveileder: 5; Biveileder: 23
Pågående doktorgrader: Hovedveileder for 5 og biveileder for 5