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Bilde av Østnes Hansen, Kine
Bilde av Østnes Hansen, Kine
Institutt for farmasi kine.o.hanssen@uit.no +4777649272 48139867 Tromsø

Kine Østnes Hansen

Job description

I am an associate professor in the reseach group Natural Products and Medicinal Chemistry, with expertise in natural product isolation, characterisation and translational research in drug development. Currently, my focus is on OMICSanalysis of complex samples, such as lipidomics analysis of algal biomass.

Selected projects:

AlgScaleUP (https://www.sintef.no/prosjekter/2022/algscaleup/)

HOTBIO (https://www.hotbio.eu/)

CandRAS (https://prosjektbanken.forskningsradet.no/en/project/FORISS/331892)

 

Teaching:

 FAR-1302, FAR-3311, FAR-3312, FAR-2302

I also work as a researcher in the UiT spin-off company KinSea Lead Discovery AS (https://www.kinsea-lead-discovery.com/)

  • Sailesh Maharjan, Johan Mattias Isaksson, Krupová Monika, Teppo Rämä, Kine Østnes Hansen, Jeanette Hammer Andersen et al.:
    Metabolomics-Guided Discovery of Bipolarolides H−O, New Ophiobolin-Type Sesterterpenes with Antibacterial Activity from the Marine-Derived Fungus Uzbekistanica storfjordensis sp. nov.
    Journal of natural products 2025 DOI / ARKIV
  • Sara Maria Ullsten-Wahlund, Kine Østnes Hansen, Guillaume Axel Petit, Espen Holst Hansen, Jeanette Hammer Andersen :
    Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
    Scientific Reports 2025 DOI / ARKIV
  • Murat Kaya, Kui Yu, Kine Østnes Hansen, Mohammed Al-Dubai, Martin Vinther So̷rensen, Muhammad Mujtaba :
    Role of Invertebrate Biological Origin in Chitin Nanocrystal’s Morphology, Chirality, and Self-Assembly
    Langmuir 2025 DOI
  • Laura Schlüter, Kine Østnes Hansen, Johan Mattias Isaksson, Jeanette Hammer Andersen, Espen Holst Hansen, Jörn Kalinowski et al.:
    Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110
    Frontiers in Bioengineering and Biotechnology 2024 DOI / ARKIV
  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen et al.:
    Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
    Frontiers in Microbiology 2023 DOI / ARKIV
  • Sara Ullsten-Wahlund, Guillaume Petit, Johan Mattias Isaksson, Ida Kristine Østnes Hansen, Yannik Karl Heinz Schneider, Marte Jenssen et al.:
    Identification of New Purpuroine Analogues from the Arctic Echinodermata Pteraster militaris That Inhibit FLT3-ITD+ AML Cell Lines
    International Journal of Molecular Sciences 2022 DOI / ARKIV
  • Marte Jenssen, Venke Kristoffersen, Kumar Motiram-Corral, Johan Isaksson, Teppo Rämä, Jeanette Hammer Andersen et al.:
    Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
    Molecules 2021 DOI / ARKIV
  • Marte Jenssen, Philip Rainsford, Eric Juskewitz, Jeanette Hammer Andersen, Espen Hansen, Johan Isaksson et al.:
    Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
    Frontiers in Microbiology 2021 DOI / ARKIV
  • Kine Østnes Hansen, Ida Kristine Østnes Hansen, Céline Sarah Marine Richard, Marte Jenssen, Jeanette Hammer Andersen, Espen Holst Hansen :
    Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons
    Natural Product Communications 2021 DOI / ARKIV
  • Venke Kristoffersen, Marte Jenssen, Heba Raid Jawad, Johan Isaksson, Espen Hansen, Teppo Rämä et al.:
    Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
    Molecules 2021 DOI / ARKIV
  • Ida Kristine Østnes Hansen, Tomas Lövdahl, Danijela Simonovic, Kine Østnes Hansen, Aaron John Christian Andersen, hege Devold et al.:
    Antimicrobial activity of small synthetic peptides based on the marine peptide turgencin A: Prediction of antimicrobial peptide sequences in a natural peptide and strategy for optimization of potency
    International Journal of Molecular Sciences 2020 DOI / ARKIV
  • Ida Kristine Østnes Hansen, Johan Isaksson, Aaron G. Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline Sarah Marine Richard et al.:
    Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
    Marine Drugs 2020 DOI / ARKIV
  • Yannik Karl-Heinz Schneider, Marte Jenssen, Johan Isaksson, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Hansen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. juillet 2020 DOI / ARKIV
  • Raja Priyanka Mary Michael Siranjeevi, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
    Natural Product Research 2019 DOI / ARKIV
  • Kine Østnes Hansen, Jeanette hammer Andersen, Annette Bayer, Sunil Kumar Pandey, Marianne Lorentzen, Kåre Bredeli Jørgensen et al.:
    Kinase chemodiversity from the Arctic: the breitfussins
    Journal of Medicinal Chemistry 2019 DOI / ARKIV
  • Yannik Karl-Heinz Schneider, Kine Østnes Hansen, Johan Isaksson, Sara Maria Ullsten-Wahlund, Espen Hansen, Jeanette Hammer Andersen :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 DOI / ARKIV
  • Aitor Moreno, Kine Østnes Hansen, Johan Isaksson :
    CSSF-CLIP-HSQMBC: measurement of heteronuclear coupling constants in severely crowded spectral regions
    RSC Advances 2019 DOI / ARKIV
  • Kine Østnes Hanssen, Johan Isaksson, Eirin Glomsaker, Jeanette hammer Andersen, Espen Hansen :
    Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum
    Molecules 2018 DOI / ARKIV
  • Justine Chervin, Marc Stierhof, Ming Him Tong, Doe Peace, Kine Østnes Hanssen, Dagmar S. Urgast et al.:
    Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time
    Journal of natural products 2017 DOI
  • Raja Priyanka Mary Michael Siranjeevi, Kine Østnes Hanssen, Johan Isaksson, Jeanette hammer Andersen, Espen Hansen :
    A Novel Brominated Alkaloid Securidine A, Isolated from the Marine Bryozoan Securiflustra securifrons
    Molecules 2017 DOI / ARKIV
  • Kine Østnes Hansen, Johan Isaksson, Annette Bayer, Jostein a Johansen, Jeanette hammer Andersen, Espen Hansen :
    Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons
    Journal of natural products 2017 DOI
  • Eva Sonnenschein, Marc Stierhof, Stephan Goralczyk, Floriane M. Vabre, Leonie Pellissier, Kine Østnes Hanssen et al.:
    Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040
    Tetrahedron 2017 DOI
  • Chiara Lauritano, Jeanette hammer Andersen, Espen Hansen, Marte Albrigtsen, Laura Escalera, Francesco Esposito et al.:
    Bioactivity Screening of Microalgae for Antioxidant, Anti-Inflammatory, Anticancer, Anti-Diabetes, and Antibacterial Activities
    Frontiers in Marine Science 2016 DOI / ARKIV
  • Lindon Moodie, Monika Zuzek, Robert Frangez, Jeanette hammer Andersen, Espen Hansen, Elisabeth Klungerbo Olsen et al.:
    Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission
    Organic and biomolecular chemistry 2016 DOI / ARKIV
  • Ove Bergersen, Kine Østnes Hanssen, Terje Vasskog :
    Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate
    Environmental Sciences Europe 2015 DOI / ARKIV
  • Kine Østnes Hanssen, Gunnar Cervin, Rozenn Trepos, Julie Petitbois, Tor Haug, Espen Hansen et al.:
    The Bromotyrosine Derivative Ianthelline Isolated from the Arctic Marine Sponge Stryphnus fortis Inhibits Marine Micro- and Macrobiofouling
    Marine Biotechnology 2014 DOI
  • Kine Østnes Hanssen, Bruno Schuler, Antony J. Williams, Taye B. Demissie, Espen Hansen, Jeanette hammer Andersen et al.:
    A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi
    Angewandte Chemie International Edition 2012 DOI
  • Kine Østnes Hanssen, Jeanette hammer Andersen, Trine Stiberg, Richard Alan Engh, Johan Svenson, Anne-Marie Genevière et al.:
    Antitumoral and Mechanistic Studies of Ianthelline Isolated from the Arctic Sponge Stryphnus fortis
    Anticancer Research 2012
  • Ove Bergersen, Kine Østnes Hanssen, Terje Vasskog :
    Anaerobic treatment of sewage sludge containing selective serotonin reuptake inhibitors
    Bioresource Technology 2012 DOI
  • Sunniva Hanset Monsø, Ida Kristine Østnes Hansen, Kine Østnes Hansen, Klara Stensvåg, Tor Haug :
    Exploring Arctic sponges for antimicrobial compounds
    2024
  • Hosea Isanda Masaki, Yannik Karl Heinz Schneider, Kine Østnes Hansen, Teppo Rämä :
    FUNGAL DIVERSITY IN MARINE SEDIMENTS AND FUCUS VESICULOSUS OF THE TROMSO HÅKØYA FJORD, TROMSØ (LOW ARCTIC)
    2024
  • Hosea Isanda Masaki, Kine Østnes Hansen, Yannik Karl Heinz Schneider, Teppo Rämä :
    Unleashing the potent secondary metabolite arsenal of Acremonium synnematoferum: A Fucus vesiculosus-associated fungus
    2024
  • Marit Huizer, Kristine Haugland, Agnethe Hansen Bæverud, Jon Brage Svenning, Kine Østnes Hansen, Espen Holst Hansen et al.:
    LC-Orbitrap MS/MS based untargeted lipidomics of marine microalgae
    2023
  • Magnus Andersland Antonsen, Kine Østnes Hansen, Espen Holst Hansen, Terje Vasskog :
    Use of metabolomics to identify secondary metabolites from marine algae biomass
    2023
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette Hammer Andersen :
    HotBio - a Horizon Europe MSCA Doctoral Network in Marine Biodiscovery
    2023
  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen et al.:
    Corrigendum: Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin (Frontiers in Microbiology, (2023), 14, (1130018), 10.3389/fmicb.2023.1130018)
    Frontiers in Microbiology 2023 DOI
  • Guillaume Petit, Kine Østnes Hansen :
    A fragment to bind them all
    2023
  • Guillaume Petit, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Holst Hansen, Annette Bayer, Bengt Erik Haug et al.:
    A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
    2023
  • Hosea Isanda Masaki, Lars Ganzert, Kine Østnes Hansen, Teppo Rämä :
    UNCULTIVABLE MARINE MICROBIOMES AND BIOACTIVE COMPOUNDS EXPLORATION
    2023
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette hammer Andersen :
    Nye legemidler fra havet?
    04. janvier 2020 FULLTEKST
  • Marte Jenssen, Jeanette Hammer Andersen, Teppo Rämä, Espen Holst Hansen, Kine Østnes Hansen, Chun Li :
    Biodiscovery of Antimicrobial Compounds from Arctic Marine Microorganisms
    2019
  • Priyanka Michael, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
    2019
  • Anette O. Siiri, Kine Østnes Hanssen, Trine Stiberg, Bernt Igeland, Terje Vasskog, Johan Svenson et al.:
    Isolation and characterization of Ianthelline from an arctic sponge
    2011

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