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Bilde av Svendsen, John Sigurd Mjøen
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Bilde av Svendsen, John Sigurd Mjøen
Fakultetsleiinga og stab NT-fak john-sigurd.svendsen@uit.no +4777644086 Tromsø You can find me here

John Sigurd Mjøen Svendsen

Job description

Professor, CSO Amicoat AS

  • Eskil André, Mattias, Adam, Anders Oskar, John Sigurd Mjøen :
    Antifouling Efficacy on S. epidermidis of Nano-Au Surfaces Functionalized with Polyethylene Glycol (PEG)-Tethered Antimicrobial Peptides
    ACS Applied Bio Materials (AABM) 2025 DOI / ARKIV
  • Adam, Eskil André, Wenche Gunvor B, John Sigurd Mjøen, Mattias, Anders :
    Preventing E. coli Biofilm Formation with Antimicrobial Peptide-Functionalized Surface Coatings: Recognizing the Dependence on the Bacterial Binding Mode Using Live-Cell Microscopy
    ACS Applied Materials & Interfaces 2024 DOI / ARKIV
  • Philip Ben, Fredrik G., Martin, Mitchell, Eric, Johanna Ulrica et al.:
    Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis
    Scientific Reports 2023 DOI / ARKIV
  • Mattias, Jorunn Pauline, Josefin Seth, Balmukund, Jeddah Marie, Wenche Gunvor B et al.:
    Flexible and Biocompatible Antifouling Polyurethane Surfaces Incorporating Tethered Antimicrobial Peptides through Click Reactions
    Macromolecular Bioscience 2023 DOI / ARKIV
  • Martin, Fredrik G., Philip, Mitchell, Maxim, Tone et al.:
    Goldilocks Dilemma: LPS Works Both as the Initial Target and a Barrier for the Antimicrobial Action of Cationic AMPs on E. coli
    Biomolecules 2023 DOI / ARKIV
  • Adéla, Sourav, Josef, Niels A. W. de, Mariella, Jonne van der et al.:
    Lateral membrane organization as target of an antimicrobial peptidomimetic compound
    Nature Communications 2023 DOI / ARKIV
  • Bangfu, Tom, Wenche Gunvor Berg, John Sigurd Mjøen, Anders, James W.L. :
    DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes
    Frontiers in Pharmacology 2022 DOI / ARKIV
  • Anne Sofie, Franziska Angelika, Lars, Niels, John Sigurd Mjøen, Wenche Gunvor Berg et al.:
    Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds
    Journal of Global Antimicrobial Resistance 2022 DOI / ARKIV
  • Joakim, Jorunn Pauline, Wenche Gunvor Berg, Bjarte, John Sigurd Mjøen, Johan :
    In vitro and in vivo antibacterial properties of peptide AMC-109 impregnated wound dressings and gels
    Journal of antibiotics (Tokyo. 1968) 2021 DOI
  • Eskil André, Wenche, Eric, Johan, Mattias, John Sigurd Mjøen :
    Anti-Colonization Effect of Au Surfaces with Self-Assembled Molecular Monolayers Functionalized with Antimicrobial Peptides on S. epidermidis
    Antibiotics 2021 DOI / ARKIV / FULLTEKST
  • Wenche, Ulli, Richard Alan, Melissa R., Ilya, Alberto C. S. et al.:
    Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome
    Pharmaceuticals 2021 DOI / ARKIV / FULLTEKST
  • Worku, Johan, Fredrik G., Petr, Eva, Sang Un et al.:
    Anti-proliferative activity of a novel tricyclic triterpenoid acid from Commiphora africana resin against four human cancer cell lines
    Applied Biological Chemistry 2020 DOI / ARKIV
  • Jacobus Johannes, Dominik, Terje, Øystein, John Sigurd Mjøen :
    Selective intracellular delivery of thiolated cargo to tumor and neovasculature cells using histidine-rich peptides as vectors
    ACS Omega 2020 DOI / ARKIV
  • John Sigurd Mjøen, Thomas M, David, Margaret A., Johan :
    Very Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design Principles and Potential Uses
    Accounts of Chemical Research 2019 DOI
  • Balmukund, John Sigurd Mjøen, Richard Alan :
    Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization
    Molecules 25. septembre 2018 DOI / ARKIV / FULLTEKST
  • Balmukund, Marte, John Sigurd Mjøen, Jeanette hammer, Richard Alan :
    Biofocussed chemoprospecting: An efficient approach for drug discovery
    Chemical Biology and Drug Design (CB&DD) 13. juin 2017 DOI / FULLTEKST
  • Balmukund, John Sigurd Mjøen, Richard Alan :
    Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion and Relevance to Peptidic Systems
    Journal of Physical Chemistry A 15. août 2017 DOI / FULLTEKST
  • Wenche, Rob, Marc, Nahid, John Sigurd Mjøen, Johan :
    Short Cationic Antimicrobial Peptides Display Superior Antifungal Activities toward Candidiasis and Onychomycosis in Comparison with Terbinafine and Amorolfine
    Molecular Pharmaceutics 2016 DOI
  • Bengt Erik, Ketil Andre, liv tone, Wenche, John Sigurd Mjøen, Kristel et al.:
    Discovery of a 9-mer cationic peptide (LTX-315) as a potential first in class oncolytic peptide
    Journal of Medicinal Chemistry 2016 DOI
  • Ulli, Wenche, Bjørn Olav, Johan, Frederick Alan, Richard Alan et al.:
    Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules
    Journal of Medicinal Chemistry 2016 DOI
  • Jacobus Johannes, Dominik, Jaione, Trine, Cristiane de Albuquerque Cavalcanti, Imin et al.:
    Iterative design and in vivo evaluation of an oncolytic antilymphoma peptide
    Journal of Medicinal Chemistry 2016 DOI
  • Ulli, Jonas, Wenche, Frederick Alan, Richard Alan, John Sigurd :
    Luciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitors
    European Journal of Medicinal Chemistry 2015 DOI
  • Annfrid, Johan, Hanna-Kirsti S., Johan, John Sigurd, Bjørn Olav :
    Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin
    BMC Structural Biology 2014 DOI / ARKIV
  • Rozenn, Gunnar, Claire, Henrik Pavia, Wenche, Klara et al.:
    Antifouling compounds from the sub-arctic ascidian synoicum pulmonaria: Synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues
    Journal of natural products 2014 DOI
  • Olga Vladimirovna, John Sigurd, Tore :
    Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics
    Journal of Peptide Science 2014 DOI
  • Alexey Sergeevich, Olga Vladimirovna, John Sigurd, Anna A., Victor V., George V. et al.:
    Boron containing peptidomimetics – a novel class of selective anti-tubercular drugs
    Chemical Biology and Drug Design (CB&DD) 2013 DOI
  • Xiaojun, Kathrin Helen, Jana, Johan, Jana, Wenche et al.:
    Determination of Absolute Configuration and Conformation of a Cyclic Dipeptide by NMR and Chiral Spectroscopic Methods
    Journal of Physical Chemistry A 2013 DOI
  • Alexey Sergeevich, Olga Vladimirovna, John Sigurd, George V., Anna A., Victor V. et al.:
    Syntheses and anti-tubercular activity of β-substituted and α,β-disubstituted peptidyl β-aminoboronates and boronic acids
    Journal of Peptide Science 2013 DOI
  • Taye B., Michal, Stanislav, Johan, John Sigurd, H et al.:
    Four-component relativistic chemical shift calculations of halogenated organic compounds
    Journal of Physical Organic Chemistry 2013 DOI
  • Annfrid, Bjørn Olav, John Sigurd, Jeanette hammer, Johan :
    Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity
    Journal of Molecular Recognition 2013 DOI
  • Kine Østnes, Bruno, Antony J., Taye B., Espen, Jeanette hammer et al.:
    A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi
    Angewandte Chemie International Edition 2012 DOI
  • Xiaojun, Kathrin Helen, Jana, Wenche, Jana, Marie et al.:
    Absolute Configuration of a Cyclic Dipeptide Reflected in Vibrational Optical Activity: Ab Initio and Experimental Investigation
    Journal of Physical Chemistry A 2012 DOI
  • Kathrin Helen, Jaroslav, Jana, Wenche, Marie, Johan et al.:
    Determining the Absolute Configuration of Two Marine Compounds Using Vibrational Chiroptical Spectroscopy
    Journal of Organic Chemistry 2012 DOI
  • Rasmus Tørnes, Geir Villy, Evelien, Yngve, Bart De, Bjørn Olav et al.:
    Targeting the S1 and S3 Subsite of Trypsin with Unnatural Cationic Amino Acids Generates Antimicrobial Peptides with Potential for Oral Administration
    Journal of Medicinal Chemistry 2012 DOI
  • Gøril Eide, Gabor, Wenche, Geir Villy, Rasmus Tørnes, John Sigurd et al.:
    In Vitro Characterization of Human Peptide Transporter hPEPT1 Interactions and Passive Permeation Studies of Short Cationic Antimicrobial Peptides
    Journal of Medicinal Chemistry 2011 DOI
  • Johan, Bjørn Olav, Stig Olov Magnus, Gøril Eide, John Sigurd, Wenche :
    A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption
    Journal of Medicinal Chemistry 2011 DOI
  • Derk, John Sigurd, Dag :
    Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic n glycans in alpha-mannosidosis: a method of monitoring treatment
    The Journal of Inherited Metabolic Disease (JIMD) 2011 DOI
  • Finn-Eirik, Trygve, Marie Hjelmseth, Alexandra, Liv Eggset, Rune et al.:
    Centre for Digital Life Norway - Annual report 2017
    Senter for Digialt Liv Norge 2018 ARKIV
  • John Sigurd Mjøen :
    Panel: Are new antibiotics the solution to the AMR threat?
    2018
  • John Sigurd Mjøen :
    Hva betyr antibiotikakrisen for kreftpasienter
    2018
  • John Sigurd Mjøen :
    Paneldebatt: Antibiotikaresistens og kreft
    2018
  • Claire, Henrik, Tor, Wenche, Klara, John Sigurd et al.:
    Antifouling compounds from the sub-Arctic ascidian Synoicum pulmonaria
    2014
  • Inger Greve, Torbjørn, John Sigurd :
    - Kan bidra til utviklingen av nye medisiner
    13. mars 2014 FULLTEKST
  • Inger Greve, Torbjørn, John Sigurd :
    Lager digitalt oppslagsverk over alt liv på jorda
    13. mars 2014 FULLTEKST
  • Inger Greve, Torbjørn, John Sigurd :
    DNA fra planter og dyr kan gi kunnskap om sykdommer
    13. mars 2014 FULLTEKST
  • Balmukund, John Sigurd Mjøen, Richard Alan :
    Design and Synthesis of diverse Piperazine-2,5-diones and their uncyclized analogues as potential kinase inhibitors
    2013
  • Kine Ø., Bruno, Antony J., Taye B., Espen, Jeanette hammer et al.:
    Introducing Atomic Force Microscopy in Structure Elucidation
    2013
  • Geir Villy, Johan, John Sigurd, Bjørn Olav :
    Structural studies of small cationic antimicrobial peptides by NMR and computer simulations have facilitated a refined pharmacophore model able to predict activity versus Staphylococcus aureus
    2011
  • Johan, Gøril Eide, Bjørn Olav, John Sigurd :
    Studies of Small Synthetic Anti-microbial Peptides by NMR and Molecular Modeling
    2010
  • Geir Villy, Rasmus Tørnes, Johan Mattias, Johan, John Sigurd, Bjørn Olav :
    Structure of short cationic antimicrobial peptides and their interactions with membranes as revealed by MD simulations
    2010

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