Disputas- Cand. med. Anders Lund Selli

Avhandlingen er tilgjengelig her! The doctoral thesis! Prøveforelesning over oppgitt emne holdes kl. 1015, samme sted:   “Life threatening hypothermia - from cell signaling of cyclic nucleotides in the cardiovascular system to its clinical implications”. Prøveforelesningen vil også bli strømmet/the trail lecture will also be streamed. Disputasen starter kl. 1215, og vil bli strømmet her. Opptak av disputasen vil være tilgjengelig i et døgn. The defense will be streamed here.  A recording of the disputation will be available for 24 hours.

Populærvitenskapelig sammendrag av avhandlingen:

Hypothermia, defined as a core temperature below 35°C, is a dangerous condition due to risk of heart failure and heart rhythm disturbances. Little research exists on medical treatment to prevent such complications in the heart and circulatory system at low temperatures, as drugs are developed for use in normothermic patients. Therefore, clinicians lack solid recommendations on how to treat hypothermic patients.
In this thesis, investigations were carried out to reveal how well-known drugs work at temperatures down to 20°C. In addition, investigations of whether the drugs increase risk of heart rhythm disturbances were performed. This is especially important in the treatment of hypothermic patients, as hypothermia itself increases the risk of heart rhythm disturbances.

Our goal was to provide more information, to create a foundation for safe and efficient use of drugs to treat hypothermic patients, with the ultimate goal of improved survival in this patient group.

Hovedveileder
Professor Erik Sveberg Dietrichs, UiO. 

Biveileder
Førsteamanuensis Ole Martin Fuskevåg, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Førsteamanuensis Brage Håheim, Institutt for biologisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet. 

Bedømmelseskomité
M.D. Ph.d. Peter Paal, Krankenhaus Barmherzige Brüder Salzburg, Østerrike - 1. opponent.
Ph.d. Maria Pura Hortigon-Vinagre, Universidad de Extremadura, Spania - 2. opponent.
Professor Inigo Zubiavrre Martinez, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet - leder av komité.

Disputasleder: Professor Peter McCourt, Institutt for biologisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.